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. 2020 May 4;96(1137):399–402. doi: 10.1136/postgradmedj-2020-137738

Table 1.

Dosages of antiviral agents for COVID-19

Medication Normal renal function
(CrCl >50 mL/min)
Impaired renal function
(CrCl 25–50 mL/min)
Hemodialysis or CrCl <20 mL/min
Lopinavir/ritonavir Lopinavir/ritonavir 400 mg/100 mg po every 12 hours Same dose Same dose
Hydroxychloroquine Hydroxychloroquine 400 mg po 24 hours Data not available Data not available
Interferon-β1b 0.25 mg/mL subcutaneous injection qEOD Data not available Data not available
Remdesivir 200 mg loading dose on day 1 is given, followed by 100 mg intravenously once per day maintenance doses Same dose Same dose

CrCl, creatinine clearance; po, by mouth.