FIGURE 6.

Absolute cell counts of neutrophil progenitors gated based on CD11b/CD16 expression as measured in the ER and over time (longitudinal). Flow cytometric measurements were done in the ER using peripheral blood from patients with other diagnoses categorized as bacterial (n = 84) or viral (n = 17) infections and coronavirus disease 2019 (COVID-19) patients as a total group (n = 103) and categorized according to the WHO classification system for COVID-19 as moderate (n = 10), severe (n = 16), or critical (n = 77) disease. A group of healthy controls (n = 23) was also included. Longitudinal measurements were done with peripheral blood from patients on the COVID-19 ward (n = 78) who were categorized as having moderate or critical disease. For the majority of patients multiple measurements were done overtime. (A) Promyelocyte counts in the ER; (B) promyelocyte counts longitudinal; (C) myelocyte counts on the ER; (D) myelocyte counts longitudinal; (E) metamyelocyte counts on the ER; and (F) metamyelocyte counts longitudinal. Results of the statistical analysis are shown in Supporting Information Table S1.3. Data are represented as individual dots with medians and interquartile range (IQR; ER samples) or as individual data points connected with a red line to indicate paired data (longitudinal data)