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Ion mobility analysis of AD brain extract in comparison to a standard mixture. Extracted ion mobilograms for fragment ion m/z 677 and its fragment ions at m/z 579 and 461 showing relative intensities characteristic of individual peptides: mixture of the standards in molar ratio 1:1:1(A), brain extract (B). Ion at m/z 677 was generated by CID in trap (24 V) from [M+3H]3+ ion selected in quadrupole, and was fragmented after ion mobility separation (10 passes) in transfer (25 V).
