Table 2.
Descriptive statistics of clinical outcomes in patients with alcoholic hepatitis during the pandemic and pre-pandemic.
| Factor |
Pre-Pandemic n=86 (%) |
Pandemic n=163 (%) |
p-value |
|---|---|---|---|
| Disease Severity | |||
| Maddrey's Score (median, IQR) | 37.45 (13.70-65.55) | 41.20 (14.30-73.80) | 0.571 |
| Steroid Use | 27 (34.6) | 23 (15.5) | 0.002 |
| Features of Decompensation | |||
| Hepatic Encephalopathy | 18 (20.9) | 55 (33.7) | 0.049 |
| Ascites | 33 (38.4) | 59 (36.2) | 0.84 |
| Paracentesis, Diagnostic | 23 (26.7) | 35 (21.5) | 0.44 |
| Paracentesis, Large Volume | 15 (17.4) | 27 (16.6) | 1.00 |
| Diuresis | 25 (29.1) | 41 (25.2) | 0.61 |
| Spontaneous Bacterial Peritonitis | 2 (2.3) | 5 (3.1) | 1.002 |
| Edema | 19 (22.1) | 37 (22.7) | 1.00 |
| Variceal Hemorrhage | 10 (11.6) | 42 (25.8) | 0.01 |
| Endoscopic Eval/Control | 18 (20.9) | 48 (29.4) | 0.20 |
| Critical Care Needs | |||
| Supplemental Oxygen | 9 (10.5) | 35 (21.5) | 0.047 |
| Ventilator Support | 9 (10.5) | 28 (17.3) | 0.21 |
| Vasopressor Support | 5 (5.8) | 29 (17.8) | 0.012 |
| Initiation of Hemodialysis | 4 (4.7) | 25 (15.3) | 0.012 |
| Outcomes | |||
| Mortality | 6 (7.0) | 24 (14.7) | 0.102 |
1: Man-Whitney U-Test, 2: Fisher's Test
Abbreviations: Interquartile Range-IQR