Table 4.
Multivariable analysis for clinical outcomes in patients with alcoholic cirrhosis admitted during the COVID-19 pandemic compared to pre-pandemic.
| Factor | Estimate | 95% Confidence Interval | p-value |
|---|---|---|---|
| Disease Severity | |||
| MELD-Na Score During Admission | 3.77 | 1.05, 13.46 | 0.04 |
| MELD-Na Score 6 Months Before Admission | 5.64 | 4.48, 6.80 | |
| Features of Decompensation | |||
| Hepatic Encephalopathy | 1.34 | 1.04, 1.73 | 0.02 |
| Ascites | 1.40 | 1.10, 1.79 | 0.007 |
| Paracentesis, Diagnostic | 1.18 | 0.91, 1.54 | 0.21 |
| Paracentesis, Large Volume | 1.38 | 1.05, 1.82 | 0.02 |
| Diuresis | 1.46 | 1.13, 1.89 | 0.004 |
| Spontaneous Bacterial Peritonitis | 1.88 | 1.03, 3.43 | 0.04 |
| Edema | 1.15 | 0.87, 1.52 | 0.33 |
| Variceal Hemorrhage | 1.00 | 0.76, 1.30 | 0.98 |
| Endoscopic Eval/Control | 1.19 | 0.92, 1.54 | 0.18 |
| Critical Care Needs | |||
| Supplemental Oxygen | 1.03 | 0.76, 1.39 | 0.86 |
| Ventilator Support | 1.21 | 0.86, 1.70 | 0.28 |
| Vasopressor Support | 1.68 | 1.14, 2.46 | 0.008 |
| Initiation of Hemodialysis | 1.52 | 0.99, 2.33 | 0.05 |
| Outcomes | |||
| Mortality | 2.00 | 1.33, 2.99 | 0.001 |
Abbreviations: Model for End Stage Liver Disease Sodium-MELD-Na