Skip to main content
. 2023 Mar 2;9:951704. doi: 10.3389/fcvm.2022.951704

FIGURE 6.

FIGURE 6

Targeting SMOC2 expression improves the proliferation, migration, and differentiation and exacerbates fibrosis of fibroblasts in vitro. (A,B) SMOC2 expression after sh-RNA or sh-SMOC2 infection (n = 6). (C) mRNA levels of SMOC2 after sh-RNA or sh-SMOC2 injection (n = 6). (D–G) Immunofluorescence staining of SMOC2 and α-SMA for the indicated groups (n = 6). (H,I) Representative images of the wound scratch assay at 0 and 24 h (n = 5). (J–N) Collagen I and collagen III expressions after sh-RNA or sh-SMOC2 infection in cardiac fibroblasts (n = 6). *p < 0.05 vs. the control + sh-RNA group. #p < 0.05 vs. the TGF β + sh-RNA group. n.s., non-significant.