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. 2023 Mar 2;9:951704. doi: 10.3389/fcvm.2022.951704

FIGURE 7.

FIGURE 7

Targeting SMOC2 expression ameliorates fibrosis via the ILK/p38 pathway in vitro. (A–E) Representative Western blots and quantitative results of ILK, t-AKT, p-AKT, t-JNK, p-JNK, t-p38, and p-p38 (n = 6). *p < 0.05 vs. the control + sh-RNA group. #p < 0.05 vs. the ISO + sh-RNA group. n.s., non-significant. (F) Representative images of the wound scratch assay post Ad-ILK infection. (G) Representative images of immunohistochemical staining for α-SMA (n = 4). (H–M) Representative Western blots and quantitative results post Ad-ILK infection (n = 3). *p < 0.05. n.s., non-significant. #p < 0.05 vs. the sh-RNA + Ad-GFP group. ##p < 0.05 vs. the sh-SMOC2 + Ad-GFP group.