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. 2023 Mar 2;17:1130055. doi: 10.3389/fnbeh.2023.1130055

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Copyright © 2023 Golini, Rigamonti, Raspa, Scavizzi, Falcone, Gourdon and Mandillo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Activity and regularity disruption index (RDI) during light and dark phase. Panel (A) shows the average weekly activity (±SEM) and panel (B) shows the average weekly RDI (±SEM), both over light and dark phases across the 5 weeks of experiment in male (M, blue) and female (F, red) cages of wild-type (WT) (diagonal lines) and DMSXL (filled bar) mice. N of cages per group: M WT = 10; M DMSXL = 10; F WT = 11; F DMSXL = 8. Bonferroni-corrected post-hoc tests to compare DMSXL and WT males (blue asterisks), and DMSXL and WT females (red asterisks), (***p < 0.001 nparLD test with genotype and week factors).