Table 3.
Univariate and multivariate-adjusted Cox regression models predicting the risk of death for all causes at one year
| Univariate | Multivariate-adjusted | ||||
|---|---|---|---|---|---|
| HR | p-Value | HR | p-Value | ||
| COPD | 1 | 1 | |||
| HF | 1.22 (0.96–1.55) | 0.102 | 1.13 (0.77–1.65) | 0.541 | |
| COPD + HF | 1.54 (1.16–2.03) | 0.003 | 1.74 (1.16–2.61) | 0.008 | |
| Age, ≥ 85 years | 1.82 (1.47–2.25) | < 0.001 | |||
| Male | 1.36 (1.09–1.69) | 0.005 | |||
| Normal weight | 1 | ||||
| Underweight | 1.95 (1.41–2.69) | < 0.001 | |||
| Overweight | 0.72 (0.52–0.99) | 0.045 | |||
| Smoking habit, current (versus former) | 0.61 (0.40–0.92) | 0.019 | |||
| CIRS-CI ≥ 3 | 1.66 (1.29–2.14) | < 0.001 | |||
| Presence of coronary artery disease | 1.27 (1.009–1.60) | 0.042 | |||
| Presence of chronic kidney disease | 1.40 (1.12–1.74) | 0.002 | |||
| Presence of dementia | 2.18 (1.61–2.95) | < 0.001 | 1.75 (1.06–2.90) | 0.030 | |
| Presence of cancer | 1.95 (1.39–2.73) | < 0.001 | |||
| Overt cognitive impairment (SBT score ≥ 10) | 1.91 (1.49–2.45) | < 0.001 | |||
| Probable depression (GDS score > 2) | 1.38 (1.02–1.85) | 0.033 | |||
| Clinically significant disability (BI ≤ 40) | 2.66 (2.07–3.41) | < 0.001 | |||
The multivariate model has been adjusted for anthropometric variables, smoking habit, comorbidities, overt cognitive impairment, probable depression and clinically significant disability
COPD indicates Chronic Obstructive Pulmonary Disease, HF heart failure, HR hazard ratio, CIRS-CI Cumulative Illness Rating Scale, comorbidity index, SBT short blessed test, GDS geriatric depression scale, BI Barthel index
In bold are significant variables
The Hosmer and Lemeshow Test for the multivariate adjusted model was p = 0.877