Table 1.

Genetic mutations in acute myeloid leukemia (AML)

Common mutations	Incidence		References	Novel mutations	Incidence		References
	Adult	Pediatric			Adult	Pediatric
NPM1	35%	8-10%	[13]	CTNNB1	22%	1.8%	[14,15]
DNMT3A	20%	2.1%	[16,17]	SRSF2	12.5%	<1%	[18], TARGET
RUNX1	10-15%	~2.8%	[5,19]	PTPN11	4%	6.9%	[20,21]
CEBPA	~10%	18%	[5,22]	PHF6	3%	2%	[23,18]
TP53	10%	2.1%	[24,25]	U2AF1	3.4%	<1%	[26], TARGET
GATA2	~5%	2.6%	[5]	ETV6	1.35%	2.2%	[27,28]