Figure 4.
Molecular structure of the TgATG13 HORMA domain. (a) Predicted structural model of the N-terminal HORMA domain of TgATG13. (b) Reference model human ATG101-ATG13 complex HORMA domain (PDB ID: 5C50). (c) Spindle checkpoint protein Mad2 dimer (PDB ID: 2VFX). (d) The 3D image of the N-terminal HORMA domain of TgATG13 was superimposed on the reference model ATG13 (PDB ID: 5C50). (e) The 3D image of the N-terminal HORMA domain of TgATG13 was superimposed on the Mad2 dimer (PDB ID: 2VFX). The α-helix and β-sheet of the reference model are expressed in purple and yellow, respectively. The α-helix and β-sheet of the TgATG13 HORMA domain model are expressed in yellow and green. The α-helix and β-sheet of the Mad2 dimer model are expressed in red and light blue.
