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. 2023 Mar 2;17:1125208. doi: 10.3389/fnins.2023.1125208

TABLE 4.

Volume means and standard deviations volumes for ME/CFS and long COVID for the brainstem subfields and whole brainstem and their statistical inference.

Volume in mm3 P-value 95% confidence interval
Lower Upper
Regions
ME/CFS Long COVID
Medulla 3110.3 ± 155.7↓ 3302.4 ± 696.7 0.407 -741.6 375.9
Pons 13889.5 ± 333.5↓ 14120.3 ± 2305.8 0.734 -2240.2 1712.7
Midbrain 5331.6 ± 295.5↓ 5456.1 ± 889.2 0.603 -862.9 570.2
SCP 270.01 ± 83.81↓ 292.27 ± 83.81 0.335 -88.9 39.8
Whole brainstem 22601.4 ± 488.7↓ 23171.1 ± 3750.7 0.610 -3702.7 2467.8

↓ Indicates a smaller volume in ME/CFS patients than long COVID. No significant volumetric differences were obtained between ME/CFS and long COVID. SCP, superior cerebral peduncle.