TABLE 1.
Baseline characteristics and outcomes of ICH patients with different admission blood glucose levels
| All subjects (N = 1372) | Admission blood glucose <7.8 (N = 984) | Admission blood glucose ≥7.8 (N = 388) | p‐value | |
|---|---|---|---|---|
| Age, y, Mean ± SD | 62.3 ± 11.6 | 62.2 ± 11.5 | 62.6 ± 11.9 | 0.158 |
| Male, (n, %) | 904 (65.9) | 651 (66.2) | 253 (65.2) | 0.738 |
| Hypertension, (n, %) | 957 (69.8) | 660 (67.1) | 297 (76.5) | 0.002 |
| DM, (n, %) | 281 (20.5) | 98 (10.0) | 183 (47.2) | <0.001 |
| Time from symptom onset to admission, h, median (IQR) | 3 (2, 7.5) | 3.5 (2, 8) | 3 (2, 6) | 0.012 |
| Admission SBP ≥140 mmHg, (n, %) | 1219 (88.8) | 869 (88.3) | 350 (90.2) | 0.316 |
| HBA1c ≥6.5%, (n, %) | 397 (28.9) | 158 (16.1) | 239 (61.6) | <0.001 |
| Admission blood glucose, mmol/L, median (IQR) | 6.5 (5.5, 8.1) | 5.9 (5.3, 6.6) | 9.5 (8.5, 11.5) | <0.001 |
| HBA1c, %, median (IQR) | 5.7 (5.3, 6.2) | 5.6 (5.3, 6.0) | 6.4 (5.6, 8.0) | <0.001 |
| Infratentorial hemorrhage, (n, %) | 159 (12.0) | 90 (9.5) | 69 (18.3) | <0.001 |
| Hematoma volume, ml, median (IQR) | 10.0 (4.6, 24.0) | 10.0 (4.5, 20.0) | 10.0 (4.3, 27.0) | 0.124 |
| IVH, (n, %) | 207 (15.1) | 118 (12.0) | 89 (22.9) | <0.001 |
| GCS, median (IQR) | 14 (12, 15) | 14 (13, 15) | 13 (9, 15) | <0.001 |
| Surgical treatment, (n, %) | 230 (16.8) | 129 (13.1) | 101 (26%) | <0.001 |
| Length of hospitalization, days, median (IQR) | 16.0 (11.0, 22.0) | 16.0 (12.0, 21.0) | 16.0 (9.0, 23.0) | 0.685 |
| Pulmonary infection, (n, %) | 179 (13.0) | 101 (10.3) | 78 (20.1) | <0.001 |
| 30‐day mRS (3–6), (n, %) | 821/1331 a (62.7) | 547/953 a (57.4) | 274/378 a (72.5) | <0.001 |
| 90‐day mRS (3–6), (n, %) | 679/1331 a (51.0) | 440/953 a (46.2) | 239/378 a (63.2) | <0.001 |
| In‐hospital death, (n, %) | 48 (3.5) | 23 (2.3) | 25 (6.4) | <0.001 |
| 30‐day death, (n, %) | 155/1331 a (11.6) | 74/953 a (7.8) | 81/378 a (21.4) | <0.001 |
| 90‐day death, (n, %) | 196/1331 a (14.7) | 106/953 a (11.1) | 90/378 a (23.8) | <0.001 |
Abbreviations: DM, diabetes mellitus; GCS, Glasgow Coma Scale; HbA1c, Glycosylated hemoglobin A1c; IQR indicates interquartile range; IVH, intraventricular hemorrhage; mRS, modified Rankin Scale; SBP, systolic blood pressure; SD, standard deviation.
a
41 patients lacked 30‐ and 90‐days follow‐up data, of which 31 with non‐hyperglycemia and 10 with hyperglycemia.