TABLE 3.
GO terms (molecular function, cell compartment, and biological process) most significantly represented (Bonferroni correction), from AS3 to LT comparison, performed with Cytoscape + ClueGo.
| ID | Term | Term p-value Corrected with Bonferroni step down | GO Levels | % Associated Genes |
|---|---|---|---|---|
| GO:0070013 | intracellular organelle lumen | 0.00 | [4] | 3.30 |
| GO:0003723 | RNA binding | 0.00 | [4] | 5.10 |
| GO:0043232 | intracellular non-membrane-bounded organelle | 0.00 | [4] | 3.31 |
| GO:0005829 | cytosol | 0.00 | [2, 3, 4] | 3.18 |
| GO:0022626 | cytosolic ribosome | 0.00 | [3, 4, 5, 6] | 18.80 |
| GO:0045047 | protein targeting to ER | 0.00 | [6, 7, 8] | 18.03 |
| GO:0000184 | nuclear-transcribed mRNA catabolic process, non-sense-mediated decay | 0.00 | [7, 8, 9, 10] | 16.79 |
| GO:1903561 | extracellular vesicle | 0.00 | [5] | 4.13 |
| GO:0044085 | cellular component biogenesis | 0.00 | [3] | 3.54 |
| GO:0006996 | organelle organization | 0.00 | [4] | 3.29 |
| GO:0005840 | ribosome | 0.00 | [5] | 10.80 |
| GO:0044391 | ribosomal subunit | 0.00 | [3, 6] | 12.24 |
| GO:0010629 | negative regulation of gene expression | 0.00 | [4, 5, 6] | 5.00 |
| GO:0006364 | rRNA processing | 0.00 | [6, 7, 8, 9] | 9.93 |
| GO:0034660 | ncRNA metabolic process | 0.00 | [6, 7] | 7.00 |
| GO:0006413 | translational initiation | 0.00 | [3, 6, 7, 8] | 11.48 |
| GO:0034470 | ncRNA processing | 0.00 | [6, 7, 8] | 7.56 |
| GO:0002181 | cytoplasmic translation | 0.00 | [6, 7, 8] | 12.80 |
| GO:0000956 | nuclear-transcribed mRNA catabolic process | 0.00 | [6, 7, 8, 9] | 10.81 |
| GO:0042254 | ribosome biogenesis | 0.00 | [5] | 8.47 |
| GO:0031981 | nuclear lumen | 0.00 | [5, 6] | 3.09 |
| GO:0005654 | nucleoplasm | 0.00 | [2, 6, 7] | 3.14 |
| GO:0022613 | ribonucleoprotein complex biogenesis | 0.00 | [4] | 6.85 |
| GO:0022625 | cytosolic large ribosomal subunit | 0.00 | [4, 5, 6, 7, 8] | 20.97 |
| GO:0070268 | cornification | 0.00 | [3, 4, 7, 8, 9] | 14.66 |
| GO:1903561 | extracellular vesicle | 0.00 | [5] | 3.09 |
| GO:0005882 | intermediate filament | 0.00 | [6, 7] | 7.08 |
| GO:0043588 | skin development | 0.00 | [4, 5, 6] | 5.06 |
| GO:0034363 | intermediate-density lipoprotein particle | 0.00 | [5, 6] | 80.00 |
| GO:0030216 | keratinocyte differentiation | 0.00 | [5, 6, 7] | 5.77 |
| GO:0034378 | chylomicron assembly | 0.00 | [4, 5, 8] | 38.46 |
| GO:0045095 | keratin filament | 0.00 | [7, 8] | 10.00 |
| GO:0062023 | collagen-containing extracellular matrix | 0.00 | [4, 5] | 4.61 |
| GO:0016584 | nucleosome positioning | 0.00 | [6, 7, 8, 9] | 29.41 |
| GO:0030261 | chromosome condensation | 0.00 | [8] | 11.43 |
| GO:0097549 | chromatin organization involved in negative regulation of transcription | 0.00 | [6, 7, 8, 9, 10, 11, 12] | 7.59 |
| GO:0034371 | chylomicron remodeling | 0.00 | [5, 6, 9] | 36.36 |
| GO:0099512 | supramolecular fiber | 0.00 | [4] | 3.11 |
| GO:0008544 | epidermis development | 0.00 | [4] | 4.03 |
| GO:0070325 | lipoprotein particle receptor binding | 0.01 | [4] | 17.86 |
| GO:0016607 | nuclear speck | 0.01 | [3, 4, 8, 9] | 4.09 |
| GO:0042627 | chylomicron | 0.01 | [4, 5] | 25.00 |
| GO:0016604 | nuclear body | 0.01 | [2, 3, 7, 8] | 3.13 |
| GO:0071103 | DNA conformation change | 0.01 | [6] | 4.26 |
| GO:0006397 | mRNA processing | 0.01 | [6, 7, 8] | 3.65 |
| GO:0031491 | nucleosome binding | 0.01 | [3] | 9.46 |
| GO:1903047 | mitotic cell cycle process | 0.01 | [3, 4] | 3.04 |
| GO:0030855 | epithelial cell differentiation | 0.01 | [4, 5] | 3.16 |
| GO:0050792 | regulation of viral process | 0.02 | [2, 3] | 5.61 |
| GO:0099513 | polymeric cytoskeletal fiber | 0.02 | [5, 6] | 3.18 |
| GO:0071827 | plasma lipoprotein particle organization | 0.03 | [2, 6] | 10.34 |
| GO:0034382 | chylomicron remnant clearance | 0.03 | [4, 5, 6] | 37.50 |
| GO:0043903 | regulation of biological process involved in symbiotic interaction | 0.03 | [2, 3] | 8.33 |
| GO:0016458 | gene silencing | 0.03 | [2, 5, 6, 7] | 4.56 |
| GO:1990204 | oxidoreductase complex | 0.04 | [3] | 6.78 |
| GO:0045815 | positive regulation of gene expression, epigenetic | 0.04 | [5, 6, 7] | 9.52 |
| GO:0006997 | nucleus organization | 0.04 | [5] | 5.92 |
| GO:0034361 | very-low-density lipoprotein particle | 0.05 | [5, 6] | 17.39 |
| GO:0006323 | DNA packaging | 0.05 | [7] | 4.60 |