Table 1.
Assay performance.
| LLOD | LLOQ | ULOQ | Median conc (Q1-Q3) | CV for QC samples | |
|---|---|---|---|---|---|
| pTau181 (pg/mL) | 0.08 | 0.46 | 990 | 1.7 (1.2–2.6) | 8% |
| tTau (pg/mL) | 0.07 | 0.63 | 2,000 | 10.2 (8.2–13.4) | 4–7% |
| NfL (pg/mL) | 2.6 | 9.6 | 5,300 | 75 (50–116) | 9–13% |
| GFAP (pg/mL) | 8.8 | 52 | 10,400 | 170 (119–228) | 5–10% |
pTau181, phosphorylated-Tau181; tTau, total Tau; NfL, neurofilament light; GFAP, glial fibrillary acidic protein; LLOD, lower level of detection; L/ULOQ, lower/upper level of quantification; Q1/Q3, Quartile 1/3; CV, coefficient of variation; QC, quality control.