|
Age, years
|
62.3±10.2
|
67.2±10.8
|
<0.001
|
|
Female sex
|
613 (21.4%)
|
2,470 (28.6%)
|
<0.001
|
|
Race
|
|
|
<0.001
|
|
White
|
1,170 (43.8%)
|
3,677 (44.5%)
|
|
|
African American
|
222 (8.3%)
|
883 (10.7%)
|
|
|
Asian
|
616 (23.0%)
|
1,573 (19.0%)
|
|
|
Hispanic
|
490 (18.3%)
|
1,728 (20.9%)
|
|
|
Other
|
175 (6.5%)
|
404 (4.9%)
|
|
|
BMI, kg/m2
|
29.1±5.4
|
28.6±5.5
|
<0.001
|
|
Clinical history
|
|
Hypertension
|
2,674 (93.5%)
|
8,121 (93.9%)
|
0.468
|
|
Hyperlipidaemia
|
2,692 (94.1%)
|
8,111 (93.8%)
|
0.517
|
|
Family history of coronary artery disease
|
768 (26.9%)
|
1,941 (22.4%)
|
<0.001
|
|
Diabetes mellitus
|
1,472 (51.5%)
|
4,196 (48.5%)
|
0.006
|
|
Insulin-dependent diabetes
|
517 (35.1%)
|
1,399 (33.3%)
|
0.214
|
|
Prior MI
|
850 (29.7%)
|
1,894 (21.9%)
|
<0.001
|
|
Prior PCI
|
1,707 (59.7%)
|
3,962 (45.8%)
|
<0.001
|
|
Prior CABG
|
425 (14.9%)
|
1,445 (16.7%)
|
0.02
|
|
Peripheral artery disease (PAD)
|
200 (7.0%)
|
869 (10.0%)
|
<0.001
|
|
Prior cerebrovascular disease (CVA)
|
151 (5.3%)
|
994 (11.5%)
|
<0.001
|
|
Chronic kidney disease (CKD)
|
560 (19.6%)
|
2,562 (29.6%)
|
<0.001
|
|
Dialysis
|
54 (1.9%)
|
346 (4.0%)
|
<0.001
|
|
Anaemia
|
1,030 (37.0%)
|
3,383 (40.1%)
|
0.004
|
|
Neoplastic disease
|
143 (5.0%)
|
695 (8.0%)
|
<0.001
|
|
Acute coronary syndrome (ACS)
|
0 (0.0%)
|
0 (0.0%)
|
N/A
|
|
LVEF, %
|
55.6±9.6
|
55.7±9.8
|
0.816
|
|
Laboratory values
|
|
Total cholesterol, mmol/L
|
135.5±42.5
|
138.5±40.8
|
0.002
|
|
LDL, mmol/L
|
76.8±31.0
|
78.0±29.8
|
0.067
|
|
HDL, mmol/L
|
38.9±10.9
|
41.1±12.2
|
<0.001
|
|
Haemoglobin, baseline, g/dL
|
13.2±1.6
|
12.9±1.7
|
<0.001
|
|
Platelet, baseline, 109/L
|
202.0 [171.0-242.0]
|
196.0 [161.0-234.0]
|
<0.001
|
|
Socioeconomic parameters (insurance)
|
|
Medicare
|
720 (26.5%)
|
2,964 (36.1%)
|
<0.001
|
|
Medicaid
|
285 (10.5%)
|
844 (10.3%)
|
0.762
|
|
Private
|
1,614 (59.4%)
|
4,250 (51.8%)
|
<0.001
|
|
Military
|
4 (0.1%)
|
2 (0.0%)
|
0.037
|
|
None
|
150 (5.5%)
|
347 (4.2%)
|
0.005
|
|
Values are n (%), mean±SD or median [interquartile range]. BMI: body mass index; CABG: coronary artery bypass graft; HDL: high-density lipoprotein; LDL: low-density lipoprotein; LVEF: left ventricular ejection fraction; MI myocardial infarction; N/A: not applicable; PCI: percutaneous coronary intervention; SD: standard deviation
|
