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. 2023 Mar 20;18(15):1244–1253. doi: 10.4244/EIJ-D-22-00654

Table 6. Kaplan-Meier estimates, unadjusted, & PS-stratified hazard ratios, stratified by clopidogrel or prasugrel use.

Outcome Prasugrel (n=1,143) Clopidogrel (n=8,648) Unadjusted hazard ratio (95% CI) p-value PS-stratified hazard ratio* p-value
Death or MI 21 (2.1%) 223 (3.1%) 0.67 (0.43-1.05) 0.082 0.66 (0.38-1.13) 0.13
Death 9 (0.9%) 108 (1.5%) 0.59 (0.30-1.17) 0.133 0.57 (0.23-1.44) 0.236
Myocardial infarction 12 (1.2%) 104 (1.4%) 0.83 (0.45-1.50) 0.533 0.85 (0.44-1.67) 0.64
* Propensity score was generated using the following variables: age2, age, gender, BMI (kg/m2), current smoking status, hypertension, hyperlipidaemia, cerebrovascular disease, prior MI, prior CABG, LVEF, acute coronary syndrome, calcification-moderate/severe, chronic total occlusion, and complex PCI.
Complex PCI is defined as having one of the following criteria: total stent length ≥60 mm, total number of stents ≥3, number of lesions ≥3, number of vessels ≥3, bifurcation with ≥2 stents, or chronic total occlusion. BMI: body mass index; CABG: coronary artery bypass graft; CI: confidence interval; LVEF: left ventricular ejection fraction; MI: myocardial infarction; PCI: percutaneous coronary intervention; PS: propensity score