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. 2023 Jan 30;51(5):2151–2176. doi: 10.1093/nar/gkad026

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© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Example genes are co-regulated by Atoh7 and Otx2. Displayed are Atoh7 and Otx2 CUT&Tag genome tracks as well as the E14.5 scATAC-seq tracks of regions surrounding genes involved in the formation of the RGC (Atoh7 and Klf7), PHC (Otx2 and Neurod4), and H&A (Foxn4) lineages, as well as two genes of the Notch pathway (Hes5 and Dll4). Note that for each gene, there are multiple enhancers co-bound by Atoh7 and Otx2 (blue boxes), although there are also enhancers predominately bound by just one of them (red boxes).