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. 1986 Feb;45(2):149–155. doi: 10.1136/ard.45.2.149

Bone metabolism in rheumatoid arthritis compared with postmenopausal osteoporosis.

R M van Soesbergen, P Lips, A van den Ende, J K van der Korst
PMCID: PMC1001838  PMID: 3947143

Abstract

Calcium and bone metabolism in 29 rheumatoid arthritis (RA) patients were compared with those in 27 postmenopausal osteoporotic patients. Signs of vitamin D deficiency were found in 20 RA patients, including 12 who took recommended amounts of vitamin D in their diets and were exposed to sufficient sunlight, and in none of the osteoporotic patients. There were no signs of malabsorption. In six out of 15 patients we found increased liver enzyme activity, which may have a role in vitamin D metabolism. We propose the influence of non-steroidal anti-inflammatory drugs (NSAIDs) on vitamin D metabolism in the liver as a possible explanation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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