Table 2.
Analysis of the correlation between ALDH2 mRNA expression and clinical prognosis in LUAD patients with different clinicopathological factors by using Kaplan-Meier Plotter.
| Lung Adenocacinoma | N | Hazard ratio | p-value |
|---|---|---|---|
| Overall survival | 719 | 0.48 (0.37 − 0.61) | 8e− 10 |
| Clinicopathhological | |||
| Stage | |||
| 1 | 370 | 0.37(0.24–0.57) | 1.8e-6 |
| 2 | 136 | 0.73 (0.45 − 1.19) | 0.2032 |
| 3 | 24 | 1.84 (0.67 − 5.08) | 0.2307 |
| AJCC stage T | |||
| 1 | 123 | 0.88 (0.48 − 1.62) | 0.6878 |
| 2 | 105 | 0.36 (0.2 − 0.63) | 0.0003 |
| 3, 4 | Sample number too low for meaningful analysis | ||
| AJCC stage N | |||
| 0 | 184 | 0.49 (0.3 − 0.8) | 0.0034 |
| 1 | 44 | 0.52 (0.23 − 1.17) | 0.1056 |
| 2 | Sample number too low for meaningful analysis | ||
| AJCC stage M | |||
| 0 | 231 | 0.47 (0.31 − 0.71) | 0.0002 |
| 1 | Sample number too low for meaningful analysis | ||
| Gender | |||
| Female | 317 | 0.45 (0.3 − 0.67) | 5.8e-5 |
| Male | 344 | 0.45 (0.32 − 0.63) | 2.5e-6 |
| Smoking history | |||
| Include those never smoked | 246 | 0.5 (0.31 − 0.81) | 0.0042 |
| Only those never smoked | 143 | 0.35 (0.14 − 0.88) | 0.0191 |
| Surgery success | |||
| Only surgical margins negative | 204 | 0.41 (0.19 − 0.89) | 0.0196 |
| Chemotherapy | |||
| No | 21 | 1.53 (0.37 − 6.35) | 0.5543 |
| Yes | 36 | 6.81 (1.64 − 28.32) | 0.0035 |