Table 2. Statistically different fecal bile acids between CN and CI.
| Bile acids | Classification | Group | P-value | |
| CN (ng/g) | CI (ng/g) | |||
|
Data are expressed as median (25% quantile, 75% quantile). P-values were calculated by Student's t test or Mann-Whitney U-test. CN: normal cognition; CI: cognitive impairments; PBA: primary bile acid; SBA: secondary bile acid. | ||||
| Cholic acid | PBA | 17476.93 (3392.46, 31117.48) | 2298.26 (402.65, 15086.72) | 0.035 |
| Chenodeoxycholic acid | PBA | 13405.17 (4045.43, 23799.13) | 2222.42 (541.38, 13613.2) | 0.017 |
| Glycocholic acid | PBA | 440.68 (163.06, 1255.82) | 99.83 (39.4, 577.28) | 0.022 |
| Glycochenodeoxycholic acid | PBA | 746.89 (398.69, 1124.03) | 218.68 (100.81, 428.34) | 0.004 |
| Taurochenodeoxycholic acid | PBA | 220.9 (120.53, 407.36) | 77.85 (32.10, 223.88) | 0.022 |
| Allocholic Acid | SBA | 1591.32 (212.42, 2767.59) | 152.17 (74.74, 1402.8) | 0.039 |
| Alpha-Muricholic acid | SBA | 36.88 (19.05) | 17.45 (14.45) | 0.009 |
| Beta-Muricholic acid | SBA | 988.52 (398.5, 2676.31) | 265.4 (226.12, 1015.36) | 0.048 |
| Chenodeoxycholic Acid 24-Acyl-β-D-glucuronide | SBA | 3.14 (1.22, 9.08) | 0.39 (0.20, 4.19) | 0.039 |
| Glycohyocholic acid | SBA | 2.4 (1.36, 5.34) | 0.39 (0.34, 1.03) | 0.001 |
| Glycoursodeoxycholic acid | SBA | 268.64 (106.39, 602.2) | 28.84 (23.06, 267.43) | 0.008 |
| Lithocholic acid 3-sulfate | SBA | 2337.19 (941.51, 8830.24) | 461.87 (122.87, 3939.11) | 0.035 |
| Norcholic acid | SBA | 131.32 (84.62, 299.36) | 55.98 (35.71, 157.43) | 0.044 |
| Taurohyodeoxycholic acid | SBA | 25.91 (10.84, 120.13) | 2.44 (0.94, 33.75) | 0.013 |
| Tauroursodeoxycholic acid | SBA | 24.58 (7.75, 95.88) | 2.04 (1.15, 32.88) | 0.019 |