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. 2023 Mar 16;13:4345. doi: 10.1038/s41598-023-31382-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Evaluation of comparative urine and serum index values (I) of each patient according to the days post-symptoms onset (PSO) by using rSARS-CoV-2 Prok2-S1 protein. The index values obtained from urine and serum samples for each patient are represented by circles and when paired they are interconnected by lines, each color being specific to the collection period after the onset of symptoms Individual data were divided according to the PSO days of the collection date, i.e. at ≤ 7 days, 8 to 20 days and ≥ 21 days.