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. Author manuscript; available in PMC: 2023 Mar 16.
Published in final edited form as: Clin Chest Med. 2022 Jun;43(2):e1–e14. doi: 10.1016/j.ccm.2022.05.001

Table 1.

Acute and chronic effects of opioids on sleep

Acute Use Chronic Use
REM latency
% REM sleep
% Light (N1/N2) sleep
% Deep (N3)
Total sleep time Unchanged Unchanged
Number of arousals/sleep disturbances

Abbreviation: REM, rapid eye movement.