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. Author manuscript; available in PMC: 2023 Mar 16.
Published in final edited form as: Biochemistry. 2019 Oct 21;59(34):3098–3110. doi: 10.1021/acs.biochem.9b00784

Table 1.

List of known miR regulators for human glycogenes organized by pathway. The HUGO Genome Nomenclature Committee (HGNC) symbol is given for each gene along with the nomenclature used in the accompanying literature cited. For the miRs, Designations for -5p and- 3p are noted where specified in reference.

Pathway Gene Symbol (HGNC) Alternative symbols used in literature miRNAs
O-GlcNAc OGT O-GLCNAC, HRNT1, MGC22921, FLJ23071, OGT1 hsa-miR-485-5p36, 39, hsa-miR-10135, hsa-miR-48337, hsa-miR-200a/200b-3p38, hsa-miR-24-140, hsa-miR-42442, hsa-miR-423-5p44, hsa-miR-746
OGA MGEA5, MEA5, NCOAT hsa-miR-53947
N-linked pathway
Glycosyltransferases RPN2 SWP1, RPNII, RIBIIR, RPN-II hsa-miR-12876, hsa-miR-37877
ALG3 NOT56L, Not56, CDGS4, D16Ertd36e hsa-miR-34278
ALG12 ECM39, CDG1G hsa-miR-147a79
ALG13 GLT28D1, CXorf45, CDG1S hsa-miR-34a80
FUT8 hsa-miR-1229, hsa-miR-34a9, hsa-miR-26a53, has-miR-26b53, hsa-miR-146a8, hsa-miR-198 69
MGAT3 GNT-III hsa-miR-23a 81
MGAT4A GnT-Iva, GnT-4a hsa-miR-42442, hsa-let-7c50
Glycosidases EDEM1 KIAA0212, EDEM hsa-miR-211 82, hsa-miR-581 83, 84, hsa-miR-204 83, 84
MAN1A2 MAN1B hsa-miR-30c, hsa-miR-3614
MAN1B1 hsa-miR-125b85, 86
MANEA FLJ12838 hsa-miR-120287
O-linked pathway
Initiation GALNT1 GalNAc-T1 hsa-miR-216b21, hsa-miR-30b/30d10, hsa-miR-10a88, hsa-miR-12920
GALNT2 GalNAc-T2 hsa-let-7b89
GALNT3 GalNAc-T3, HHS, HFTC hsa-miR-26a90, hsa-miR-17-3p and hsa-miR-22191
GALNT4 GalNAc-T4 hsa-miR-426292, hsa-miR-993, hsa-miR-36594
GALNT5 GalNAc-T5 hsa-miR-196b-5p95
GALNT7 GalNAc-T7 hsa-miR-15418, hsa-miR-21411, 17, hsa-miR-30a-5p16, hsa-miR-49414, 15, hsa-miR-34a/c13, hsa-miR-17-3p/5p12, hsa-miR-21411, 17,hsa-miR-30b/30d10, hsa-miR-378 1019
GALNT10 GalNAc-T10 hsa-miR-12296
GALNT13 GalNAc-T13, KIAA1918 hsa-miR-42442

GALNT14 GalNAc-T14, FLJ12691 hsa-miR-125a97
TMTC2 DKFZp762A217 hsa-miR-14298
POGLUT1 KDELCL1, MDS010, MDS010, MGC32995, 9630046K23Rik, MDSRP, hCLP46, Rumi hsa-miR-13499, hsa-miR-14299, 100
Elongation and Branching B3GAT3 GlcAT-I hsa-miR-23b101
B3GLCT B3GALTL hsa-miR-200b, hsa-miR-200c, hsa-miR-4293
B3GNT5 B3GN-T5, beta3Gn-T5 hsa-miR-203102
C1GALT1 C1GALT, T-synthase hsa-miR-148b103
C1GALT1C1 COSMC, C1GALT2 hsa-miR-320104, hsa-miR-155105, hsa-miR-374b106
GCNT2 NACGT1, II, GCNT5, CCAT, IGNT, NAGCT1, bA421M1.1, bA360O19.2, ULG3 hsa-miR-199a/b-5p 107
GCNT3 C2GnT-M, C2/4GnT, C2GnT2 hsa-miR-302b-3p 108, hsa-miR-15b 109
LFNG SCDO3 hsa-miR-200f 110, hsa-miR-125a-5p 111, 112, hsa-miR-146a 113
Capping
PolyLacNAc B3GALT5 beta3Gal-T5, B3GalT-V, GLCT5, B3T5 hsa-miR-203114
B4GALT1 GGTB2 hsa-miR-124-3p115
Sialylation ST3GAL3 ST3Gal III, SIAT6, MRT12 hsa-miR-200a116
ST3GAL4 STZ, SAT3, FLJ11867, CGS23, SIAT4, NANTA3, SIAT4C hsa-miR-200a116, hsa-miR-370113
ST3GAL5 SIAT9, ST3GalV, SIATGM3S hsa-miR-26a117, hsa-miR-548l117, hsa-miR-34a117, hsa-miR-200b3, hsa-miR-200c3, hsa-miR-4293
ST3GAL6 SIAT10, ST3GALVI hsa-miR-26a118, 119
ST6GAL1 SIAT1, ST6Gal I hsa-miR-9120
ST6GALNAC1 SIAT7A, ST6GalNAcI hsa-miR-30d-5p121
ST6GALNAC2 SIAT7, SIAT7B, SIATL1 hsa-miR-182122, 123, hsa-miR-135b122, 123
ST6GALNAC4 SIAT7D, ST6GALNACIV, SIAT3C hsa-miR-4299124
ST6GALNAC5 SIAT7E, MGC3184, ST6GalNAcV hsa-miR-200b, hsa-miR-200c, hsa-miR-4293
ST8SIA1 SIAT8, SIAT8A hsa-miR-33a,hsa- let-7e125
ST8SIA2 SIAT8B, STX, ST8SIA-II, HsT19690 hsa-miR-3099126
ST8SIA4 SIAT8D, ST8Sia IV hsa-miR-26a/26b127, hsa-miR-146a/146b128, hsa-miR-181c128
Fucosylation FUT1 H, HSC hsa-miR-140-5p129, hsa-miR-149 129, hsa-miR-34a 130
FUT2 SE, sej, Se2, SEC2 hsa-miR-15b 131
FUT4 CD15, FUC-TIV, FCT3A, ELFT hsa-miR-125a-5p 129, hsa-miR-26a/26b 53, 56, hsa-miR-200c 55, hsa-miR-200b 55, hsa-miR-493-5p 52, hsa-miR-224-3p 51
FUT5 FUC-TV hsa-miR-125a-3p 132
FUT6 FT1A, FCT3A, FucT-VI, FLJ40754 hsa-miR-326 133, hsa-miR-125a-3p 132, hsa-miR-106b 133
FUT8* See above in N-linked pathway
GAG related enzymes
Chondroitin Sulfate Synthetases CHSY1 KIAA0990, CSS1
has-miR-194, hsa-miR-515134
CHPF CSS2, CHSY2 has-miR-194, hsa-miR-515134
CHSY3 CSS3, CHSY-2 has-miR-194, hsa-miR-515134
Glucuronyl acid epimerase GLCE KIAA0836, HSEPI hsa-miR-218135
Sulfotransferases/sulfatases CHST3 C6ST, C6ST1 hsa-miR-513a-5p 136
HS3ST2 3OST2 hsa-miR-100 137
HS6ST2 hsa-miR-141-3p, hsa-miR-145-5p 138
NDST1 HSST, NST1 hsa-miR-149139, hsa-miR-24139, hsa-miR-191139
SULF1 KIAA1077, SULF-1, hSulf-1 hsa-miR-21140
Hyaluronan synthetases
 
HAS1 HAS hsa-miR-125a141, hsa-miR-214141
HAS2 hsa-miR-410 (up-regulating) 142, hsa-miR-7143, hsa-miR-26b144, hsa-miR-378144, hsa-miR-23a-3p 145, hsa-miR-424/424*146, hsa-miR-23147, hsa-miR-574147, hsa-miR-101-3p148
HAS3 hsa-miR-26a-5p149, hsa-miR-29a-3p150
Others
Glycosidases
 
 
 
FUCA2 MGC1314, dJ20N2.5 hsa-miR-145151, hsa-miR-200b, hsa-miR-200c, hsa-miR-429 4
GALC hsa-miR-140-5p152
GBA GLUC, GBA1 hsa-miR-22-3p153
NEU1 NEU hsa-miR-125b154
HEXB hsa-miR-207, hsa-miR-352 155
Nucleotide Sugar Metabolism
 
PMM2 CDG1, CDGS, CDG1a, PMI, PMI1 hsa-miR-451a156, 157
TSTA3 FX, P35B, SDR4E1 hsa-miR-125a-5p, hsa-miR-125b158
CMAHP CMAH hsa-miR-155-5p, hsa-miR-425-5p, hsa-miR-15a-5p, hsa-miR-503-5p, hsa-miR-16-5p, hsa-miR-29a-3p, and hsa-miR-29b-3p159
UAP1 SPAG2, AGX1, AgX hsa-miR-224-5p 160
Nucleotide sugar transporters
SLC35B2 PAPST1, UGTrel4 hsa-miR-22161
SLC35B4 FLJ14697, YEA4 hsa-miR-1764, hsa-miR-1700162
SLC35F5 FLJ22004 hsa-miR-369-3p 163
UDP-Glucuronyltransferases (involved in Drug Metabolism) UGT2B15 UGT2B8 hsa-miR-331-5p164, 165, hsa-miR-376c 166, hsa-miR-770-5p 165, hsa-miR-103b 165, hsa-miR-3924 165, hsa-miR-376b-3p 165, hsa-miR-455-5p, 165 hsa-miR-605 165, hsa-miR-624-3p 165, hsa-miR-4712-5p 165, hsa-miR-3675-3p 165, hsa-miR-6500-5p 165, hsa-miR-548as-3p 165, hsa-miR-4292 165
UGT2B17 hsa-miR-376c 166
UGT2B7 UGT2B9 hsa-miR-1293, hsa-miR-3664-3p, hsa-miR-4317, hsa-miR-513c-3p, hsa-miR-4483, and hsa-miR-142-3p 164, 167
Other Glycosylation Related Proteins
 
 
COG6 COD2, KIAA1134 hsa-miR-1 168
KL (Klotho) hsa-miR-34a169, hsa-miR-199b-5p170, 171, hsa-miR-504172, hsa-miR-339172, hsa-miR-556173
SPOCK1 TIC1, SPOCK, testican-1 hsa-miR-150-3p/5p 174, 175, hsa-miR-129-5p 174, hsa-miR-585 175
SPOCK3 testican-3 hsa-miR-145176