Table 6.

Relationship between ALB and renal function decline in different models

Exposure	Crude model (β,95%CI, P )		Model I (β,95%CI, P )		Model II (β,95%CI, P )		Model III (β,95%CI, P )
ALB	-3.37 (-3.93, -2.82)	< 0.001	-2.65 (-3.22, -2.07)	< 0.001	-1.41 (-2.11, -0.72)	< 0.001	-1.13 (-1.83, -0.43)	< 0.05
ALB Quartile
Q1	Ref		Ref		Ref		Ref
Q2	-3.50 (-4.47, -2.53)	< 0.001	-2.59 (-3.54, -1.65)	< 0.001	-1.19 (-2.19, -0.19)	< 0.05	-1.10 (-2.10, -0.10)	< 0.05
Q3	-4.373 (-5.34, -3.40)	< 0.001	-3.37 (-4.33, -2.41)	< 0.001	-1.70 (-2.76, -0.64)	< 0.05	-1.35 (-2.41, -0.29)	< 0.05
Q4	-4.811 (-5.72, -3.90)	< 0.001	-3.60 (-4.55, -2.66)	< 0.001	-1.91 (-2.99, -0.83)	< 0.001	-1.49 (-2.58, -0.41)	< 0.05
P for trend	< 0.001		< 0.001		< 0.001		< 0.05

Crude model: we did not adjust other covariants

Model I: we adjust age, history of CVD, BMI, gender, SBP, diabetes, hypertension, and etiology of CKD

Model II: we adjust age, BMI, gender, SBP, diabetes, use of calcium channel blocker, hypertension, etiology of CKD, UPCR, history of CVD, eGFR, urinary occult blood, Hb, use of RAAS inhibitor, use of diuretics

Model III: we adjust age (smooth), etiology of CKD, gender, history of CVD, use of RAAS inhibitor, eGFR (smooth), SBP (smooth), BMI (smooth), hypertension, diabetes, UPCR (smooth), use of calcium channel blocker, Hb (smooth), urinary occult blood, use of diuretics

CI Confidence, Ref Reference