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. 2023 Mar 16;14:29. doi: 10.1186/s40104-023-00841-4

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Effects of DON on the expression of ferroptosis-related genes in duodenum. The relative mRNA abundance of ferroptosis-related genes in duodenum (A). Values are expressed as means ± SD, n = 7. A representative image (B) and the relative density (C) of protein bands of ferroptosis-related proteins in duodenum. Values are expressed as means ± SD, n = 3. Labeled means without a common letter differ, P < 0.05. Control, base diet; 1.0 DON, basal diet supplemented with 1.0 mg/kg DON; 3.0 DON, basal diet supplemented with 3.0 mg/kg DON. ACSL4, acyl-CoA synthetase long chain family member 4; ALOX5, arachidonate 5-lipoxygenase; ALOX12, arachidonate 12-lipoxygenase, 12S type; ALOX15, arachidonate 15-lipoxygenase; CISD1, CDGSH iron sulfur domain 1; DMT1, divalent metal transporter 1; FTL, ferritin light chain; FPN, ferroportin; FTH1, ferritin heavy chain 1; FSP1, ferroptosis suppressor protein 1; GPX4, glutathione peroxidase 4; HSPB1, heat shock protein family B (small) member 1; SLC7A11, solute carrier family 7 member 11; STEAP3, six-transmembrane epithelial antigen of prostate 3; TFR1, transferrin receptor