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. 2023 Mar 15;17(1):19. doi: 10.1186/s13065-023-00929-y

Table 3.

Assay results for determination of ASP, ATR and RAM drugs in pure forms by the proposed micellar HPLC method

Compound Proposed method Comparison method [9]
Amount taken, (µg/mL) % Found % Found
ASP 1 100.20 99.37
40 100.59 100.83
100 99.94 99.69
150 101.91
200 98.85
Mean ± SD 100.31 ± 1.11 99.69 ± 0.77
t-test 0.45 (2.45)
F- test 2.09 (19.25)
ATR 0.5 99.00 99.05
40 100.63 101.34
100 99.74 99.49
150 101.05
200 99.55
Mean ± SD 99.99 ± 0.83 99.96 ± 1.22
t-test 0.05 (2.45)
F-test 2.13 (6.95)
RAM 5 100.86 101.03
20 99.53 98.73
60 99.43 100.46
80 98.94
100 100.72
Mean ± SD 99.91 ± 0.85 100.07 ± 1.21
t-test 0.25 (2.45)
F-test 2.00 (6.95)