Table 2.
Individual HSV1 loci that appear to discriminate between virulent and attenuated clusters
|
Gene |
Gene function* |
AA differences† |
% AA similarity |
Gene differences† |
% Gene similarity |
Gene length |
|---|---|---|---|---|---|---|
|
RL1 |
Neurovirulence factor ICP34.5 |
47 |
81.1 % |
90 |
88.3 % |
768 bp |
|
UL21 |
Viral gene expression / egress tegument protein |
9 |
98.3 % |
25 |
98.4 % |
1607 bp |
|
UL29 |
DNA binding, synthesis |
9 |
99.2 % |
62 |
98.3 % |
3591 bp |
|
UL30 |
DNA polymerase |
13 |
98.9 % |
51 |
98.6 % |
3707 bp |
|
UL36 |
Tegument protein VP1/2 |
101 |
96.7 % |
214 |
97.7 % |
9222 bp |
|
UL51 |
Nuclear egress |
4 |
98.4 % |
13 |
98.2 % |
735 bp |
|
US6 |
Envelope glycoprotein D |
5 |
98.7 % |
21 |
98.2 % |
1185 bp |
|
US7 |
Envelope glycoprotein I |
22 |
94.5 % |
57 |
95.2 % |
1191 bp |