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Particle sizes of the spray dried powder formulations (n=3). Data is presented as mean ± standard deviation
| Formulation | D10 (μm) | D50 (μm) | D90 (μm) | Span |
|---|---|---|---|---|
|
| ||||
| Colistin alone | 1.2 ± 0.0 | 2.4 ± 0.0 | 5.2 ± 0.3 | 1.7 ± 0.1 |
| 1:1 Col a -Tob b | 1.1 ± 0.0 | 2.3 ± 0.0 | 5.0 ± 0.1 | 1.7 ± 0.0 |
| 1:5 Col-Tob | 1.1 ± 0.0 | 2.3 ± 0.0 | 5.4 ± 0.1 | 1.9 ± 0.0 |
| Tobramycin alone | 1.0 ± 0.0 | 2.3 ± 0.1 | 5.4 ± 0.4 | 2.0 ± 0.1 |
Col – colistin
Tob – tobramycin
