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. Author manuscript; available in PMC: 2023 Nov 1.
Published in final edited form as: Pharm Res. 2022 Aug 2;39(11):2781–2799. doi: 10.1007/s11095-022-03344-5

Table 3.

Percent weight and moles of colistin on the surface of spray dried combination particles determined by X-ray photoelectron spectroscopy (n=3 or 4). Data is presented as mean ± standard deviation

Formulation Percentage weight fraction of colistin Percentage molar fraction of colistin
Theoretical Experimental Theoretical Experimental

Colistin alone 100.0 99.6 ± 0.6 100.0 99.2 ± 1.1
1:1 Col a -Tob b 69.0 88.6 ± 5.0 50.0 78.0 ± 7.3
1:5 Col-Tob 31.0 76.8 ± 1.3 16.7 59.7 ± 1.5
Tobramycin alone 0.0 0.0 ± 0.1 0.0 0.0 ± 0.0
a

Col – colistin

b

Tob – tobramycin