TABLE 1.
Characteristics of carbapenemase-producing K. pneumoniae isolates from our collectiona
|
Strain |
ST | K-type | Virulence score | Definition | rmpABC | rmpA2 | iucABCD_iutA | ybt | clb | kfu | No. virulence genes | Virulence plasmids | Carbapenemase | Canton | Source | Date |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N330 | 23 | K1 | 5 | hvKp | − | +; trunc | + | + | + | + | 35 | pST23_OXA-48 | OXA-48 | VD | Rectal swab | 2018 |
| N488 | 23 | K1 | 5 | hvKp | − | +; trunc | + | + | + | + | 35 | pST23_OXA-48 | OXA-48 | VD | Rectal swab | 2019 |
| N593 | 23 | K1 | 5 | hvKp | − | − | + | + | + | + | 34 | pST23_OXA-48 | OXA-48 | VD | Rectal swab | 2019 |
| N911 | 14 | K2 | 4 | hvKp | − | +; trunc | + | + | − | + | 20 | pKpCH_aerob | OXA-48 | GE | Rectal swab | 2019 |
| N321 | 395 | K2 | 4 | hvKp | − | +; trunc | + | + | − | − | 17 | pKpCH_aerob | KPC-3 | VS | Urine | 2018 |
| N346 | 395 | K2 | 4 | hvKp | − | − | + | + | − | − | 16 | pKpCH_aerob | KPC-41 | VS | Rectal swab | 2018 |
| N447 | 395 | K2 | 4 | hvKp | − | +; trunc | + | + | − | − | 17 | pKpCH_aerob | KPC-3 | VS | Blood culture | 2018 |
| N1052 | 395 | K2 | 4 | hvKp | − | − | + | + | − | − | 16 | pKpvST147B-like | NDM-1 | TI | Urine | 2019 |
| N570 | 395 | K2 | 4 | hvKp | − | +; trunc | + | + | − | − | 17 | pKpCH_aerob | KPC-3 | VD | Tracheal fluid | 2018 |
| N732 | 395 | K2 | 4 | hvKp | − | − | + | + | − | − | 16 | pKpCH_aerob | KPC-3 | VS | Rectal swab | 2019 |
| N793 | 395 | K2 | 4 | hvKp | − | +; trunc | + | + | − | − | 17 | pKpCH_aerob | KPC-3 | BL | Urine | 2019 |
| N435 | 395 | K2 | 4 | hvKp | − | − | + | + | − | − | 16 | pKpCH_aerob | KPC-41 | VD | Rectal swab | 2018 |
| N649 | 395 | K2 | 4 | hvKp | − | +; trunc | + | + | − | − | 17 | pKpCH_aerob | OXA-48 | BE | Rectal swab | 2019 |
| N621 | 147 | K20 | 3 | nhv-Kp | + | +; trunc | + | − | − | − | 9 | pKpvST147B-like | NDM-1 | VD | Rectal swab | 2019 |
| N969 | 147 | K20 | 3 | nhv-Kp | + | +; trunc | + | − | − | − | 9 | pKpvST147B-like | NDM-1 | LU | Urine | 2019 |
| N829 | 147 | K20 | 3 | nhv-Kp | +; A_trunc | − | + | − | − | − | 8 | pKpvST147B-like | NDM-1 | LU | Urine | 2019 |
| N1259 | 147 | K20 | 3 | nhv-Kp | + | +; trunc | + | − | − | − | 9 | pKpvST147B-like | NDM-1 | LU | Urine | 2020 |
| N1498 | 147 | K20 | 3 | nhv-Kp | + | +; trunc | + | − | − | − | 9 | pKpvST147B-like | NDM-1 | SG | Urine | 2020 |
| N1712 | 147 | K64 | 4 | nhv-Kp | − | − | + | + | − | − | 16 | pKpvST147B-like | NDM-1 | ZH | Puncture | 2020 |
| N1071 | 147 | K64 | 4 | nhv-Kp | + | − | + | + | − | − | 19 | pKpvST147B-like | NDM-1 | GE | Rectal swab | 2020 |
| N1448 | 147 | K64 | 4 | nhv-Kp | + | +; trunc | + | + | − | − | 20 | pKpvST147B-like | NDM-1 | ZH | Rectal swab | 2020 |
| N1692 | 147 | K64 | 4 | nhv-Kp | − | − | + | + | − | − | 16 | pKpvST147B-like | NDM-1 | ZH | Blood culture | 2020 |
| N896 | 101 | K17 | 4 | nhv-Kp | − | +; trunc | + | + | − | + | 20 | pKpCH_aerob | KPC-3 | GE | Rectal swab | 2019 |
| N1325 | 101 | K17 | 4 | nhv-Kp | − | − | + | + | − | + | 19 | pKpCH_aerob | KPC-3 | GR | Rectal swab | 2020 |
| N608 | 16 | K51 | 4 | nhv-Kp | + | +; trunc | + | + | − | − | 20 | pKpvST147B-like | NDM-1 | VS | Rectal swab | 2019 |
a
rmpABC and rmpA2 are mucoid phenotype regulators. iucABCD_iutA is an aerobactin cluster, ybt is a yersiniabactin cluster; and clb is a colibactin cluster. kfu shows ferric iron uptake. The virulence plasmids used have the following accession numbers: pST23_OXA-48, OP690161; pKpCH_aerob, OP690162; and pKpvST147, CP040726.1. −, absence; +, presence; BE, Bern; BL, Basel-Landschaft; GE, Geneva; GR, Graubünden; LU, Lucerne; SG, St-Gallen; TI, Ticino; VD, Vaud; VS, Valais; ZH, Zürich; hvKp, hypervirulent K. pneumoniae; nhv-Kp, nonhypervirulent K. pneumoniae; trunc, truncated.