Table 4. Clinicopathologic characteristics according to biochemical cure.
| Variables | Biochemical cure | P value | ||
|---|---|---|---|---|
| Total | Yes | No | ||
| Age (years) | 0.237 | |||
| ≤50 | 68 (49.3) | 38 (45.2) | 30 (55.6) | |
| >50 | 70 (50.7) | 46 (54.8) | 24 (44.4) | |
| Gender | 0.215 | |||
| Male | 60 (43.5) | 33 (39.3) | 27 (50.0) | |
| Female | 78 (56.5) | 51 (60.7) | 27 (50.0) | |
| Tumor size (cm) | 0.198 | |||
| ≤2 cm | 98 (71.0) | 63 (75.0) | 35 (64.8) | |
| >2 cm | 40 (29.0) | 21 (25.0) | 19 (35.2) | |
| Multifocality | 0.030 | |||
| Yes | 37 (26.8) | 17 (20.2) | 20 (37.0) | |
| No | 101 (73.2) | 67 (79.8) | 34 (63.0) | |
| Extrathyroidal extension | 0.242 | |||
| Yes | 53 (38.4) | 29 (34.5) | 24 (44.4) | |
| No | 85 (61.6) | 55 (65.5) | 30 (55.6) | |
| Bilateral | 0.082 | |||
| Yes | 10 (7.2) | 3 (3.6) | 7 (13.0) | |
| No | 128 (92.8) | 81 (96.4) | 47 (87.0) | |
| Pathologic T classification | 0.096 | |||
| pT1/T2 | 81 (58.7) | 54 (64.3) | 27 (50.0) | |
| pT3/T4 | 57 (41.3) | 30 (35.7) | 27 (50.0) | |
| Preoperative calcitonin | 0.001 | |||
| ≤300 ng/L | 51 (37.0) | 40 (47.6) | 11 (20.4) | |
| >300 ng/L | 87 (63.0) | 44 (52.4) | 43 (79.6) | |
| Pathologic N classification | <0.001 | |||
| pN0 | 60 (43.5) | 51 (60.7) | 9 (16.7) | |
| pN1a | 21 (15.2) | 12 (14.3) | 9 (16.7) | |
| pN1b | 57 (41.3) | 21 (25.0) | 36 (66.7) | |
| Resected lymph nodes | <0.001 | |||
| ≤10 | 65 (47.1) | 51 (60.7) | 14 (25.9) | |
| >10 | 73 (52.9) | 33 (39.3) | 40 (74.1) | |
| Metastasized lymph nodes | <0.001 | |||
| ≤10 | 118 (85.5) | 80 (95.2) | 38 (70.4) | |
| >10 | 20 (14.5) | 4 (4.8) | 16 (29.6) | |
| Lymph node ratio | <0.001 | |||
| ≤0.24 | 73 (57.9) | 58 (76.3) | 15 (30.0) | |
| >0.24 | 53 (42.1) | 18 (23.7) | 35 (70.0) | |
| AJCC clinical stage | <0.001 | |||
| I/II | 54 (39.1) | 48 (57.1) | 6 (11.1) | |
| III/IV | 84 (60.9) | 36 (42.9) | 48 (88.9) | |
| Recurrence | 0.002 | |||
| Yes | 20 (14.5) | 6 (7.1) | 14 (25.9) | |
| No | 118 (85.5) | 78 (92.9) | 40 (74.1) | |
| Death | 0.711 | |||
| Yes | 8 (5.8) | 4 (4.8) | 4 (7.5) | |
| No | 129 (94.2) | 80 (95.2) | 49 (92.5) | |
Note:
The bold part of the P value represents P < 0.05.