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. 2023 Mar 13;11:e15025. doi: 10.7717/peerj.15025

Table 7. Univariate and multivariate Cox regression models for predicting overall survival.

Variables Univariate analysis Multivariate analysis
HR 95% CI P value HR 95% CI P value
Age ≤50 years 0.785 [0.252–2.439] 0.675
Gender, male 0.606 [0.191–1.919] 0.394
Tumor size >2 cm 4.385 [1.375–13.989] 0.012 2.847 [0.870–9.312] 0.084
Multifocality 1.536 [0.458–5.146] 0.487
Extrathyroidal extension 2.965 [0.887–9.908] 0.077
Bilateral 0.649 [0.083–5.095] 0.681
Preoperative calcitonin ≤300 ng/L 6.943 [0.881–54.724] 0.066
Pathologic T classification, pT3/T4 2.801 [0.838–9.361] 0.094
Pathologic N classification, pN0/N1a 14.947 [1.922–116.264] 0.010 4.521 [0.516–39.627] 0.173
Resected lymph nodes ≤10 64.123 [0.597–6890.514] 0.081
Metastasized lymph nodes ≤10 3.251 [0.971–10.884] 0.056
Lymph node ratio ≤0.24 15.994 [2.063–124.023] 0.008 10.061 [1.222–82.841] 0.032
AJCC clinical stage, III/IV stages 43.503 [0.332–5694.725] 0.129
Biochemical cure 1.870 [0.467–7.488] 0.376

Notes:

HR, hazard ratio; CI, confidence interval. The bold part of the P value represents P < 0.05.