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. 2023 Apr;29(4):415–422. doi: 10.1261/rna.079500.122

FIGURE 1.

FIGURE 1.

Model showing a potential mechanism for transcriptional activation or repression. The RNA:AGO:TNRC6 complex binds at a promoter to a nascent transcript (not directly to chromosomal DNA) and alters the mix of proteins necessary for gene activation or repression.