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. 2023 Mar 16;18(3):e0282688. doi: 10.1371/journal.pone.0282688

Table 3. Selected biomarkers related to COVID-19 in the two study groups (n = 139); mean (days) ± standard deviation.

Variable Study groups Baseline On discharge* Week 12*
Lactose dehydrogenase (LDH) AYUSH plus 403.6 ± 131.6 338.9 ± 109.7 318.7 ± 109.6
SOC 446.7 ± 206.5 363.8 ± 115.2 381.9 ± 164.8
LDH Reference Range: 225–480 U/L
Ferritin AYUSH plus 337.8 ± 280.3 257.7 ± 226.1 84.4 ± 70.2
SOC 337.4 ± 278 201.8 ± 206 92.5 ± 89.3
Ferritin Reference Range: Male 30–350 ng/ml; Female 20–250 ng/ml
Procalcitonin AYUSH plus 0.1 ± 0.1 0.1 ± 0.1 0.1 ± 0.2
SOC 0.1 ± 0.04 0.1 ± 0.2 0.1 ± 0.2
Prolactin Reference Range: <0.2 ng/ml
C-reactive protein AYUSH plus 20.83 ± 27.55 10.3 ± 19.1 6.3 ± 6.5
SOC 25.5 ± 35.3 10.7 ± 12.5 6.39 ± 8.98
C-Reactive Protein Reference Range <3 mg/L
D-Dimer AYUSH plus 462.5 ± 439.9 334 ± 224.9 297.3 ± 277.6
SOC 523.2 ± 672.8 345.3 ± 324.2 317.9 ± 418.4
D-Dimer Reference Range:0–400 ng/ml
Interleukin-6 AYUSH plus 30.6 ± 46.0 7.7 ± 12.2 8.5 ± 22.1
SOC 32.6 ± 42.2 8.5 ± 15.8 7.4 ± 10.3
Interleukin-6 Reference Range: Up to 7 pg/ml

*Statistically significant (P<0.05, Mann Whitney statistic) change from baseline within the study group for all variables except Pro-calcitonin

**NS Not statistically significant (P> = 0.05)

Note, Abbreviation: AYUSH plus: AYUSH 64 + Standard of Care (SOC); n = number of participants; See text for detail