Table 3. Selected biomarkers related to COVID-19 in the two study groups (n = 139); mean (days) ± standard deviation.
Variable | Study groups | Baseline | On discharge* | Week 12* |
---|---|---|---|---|
Lactose dehydrogenase (LDH) | AYUSH plus | 403.6 ± 131.6 | 338.9 ± 109.7 | 318.7 ± 109.6 |
SOC | 446.7 ± 206.5 | 363.8 ± 115.2 | 381.9 ± 164.8 | |
LDH Reference Range: 225–480 U/L | ||||
Ferritin | AYUSH plus | 337.8 ± 280.3 | 257.7 ± 226.1 | 84.4 ± 70.2 |
SOC | 337.4 ± 278 | 201.8 ± 206 | 92.5 ± 89.3 | |
Ferritin Reference Range: Male 30–350 ng/ml; Female 20–250 ng/ml | ||||
Procalcitonin | AYUSH plus | 0.1 ± 0.1 | 0.1 ± 0.1 | 0.1 ± 0.2 |
SOC | 0.1 ± 0.04 | 0.1 ± 0.2 | 0.1 ± 0.2 | |
Prolactin Reference Range: <0.2 ng/ml | ||||
C-reactive protein | AYUSH plus | 20.83 ± 27.55 | 10.3 ± 19.1 | 6.3 ± 6.5 |
SOC | 25.5 ± 35.3 | 10.7 ± 12.5 | 6.39 ± 8.98 | |
C-Reactive Protein Reference Range <3 mg/L | ||||
D-Dimer | AYUSH plus | 462.5 ± 439.9 | 334 ± 224.9 | 297.3 ± 277.6 |
SOC | 523.2 ± 672.8 | 345.3 ± 324.2 | 317.9 ± 418.4 | |
D-Dimer Reference Range:0–400 ng/ml | ||||
Interleukin-6 | AYUSH plus | 30.6 ± 46.0 | 7.7 ± 12.2 | 8.5 ± 22.1 |
SOC | 32.6 ± 42.2 | 8.5 ± 15.8 | 7.4 ± 10.3 | |
Interleukin-6 Reference Range: Up to 7 pg/ml |
*Statistically significant (P<0.05, Mann Whitney statistic) change from baseline within the study group for all variables except Pro-calcitonin
**NS Not statistically significant (P> = 0.05)
Note, Abbreviation: AYUSH plus: AYUSH 64 + Standard of Care (SOC); n = number of participants; See text for detail