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. 2023 Mar 15;62(4):55. doi: 10.3892/ijo.2023.5503

Figure 6.

Figure 6

The association between low-dose PDT-induced tumour angiogenesis and the ALK1-Smad1/5-ID1 pathway. (A and B) Expression of ALK1 in the control, PDT, K02288 and PDT + K02288 groups (scale bars, 50 µm). (C-F) Expression of ALK1, Smad 1, p-Smad1/5 and ID1 proteins in the control, PDT, K02288 and PDT + K02288 groups. (G-J) Expression of ALK1, Smad 1, p-Smad1/5 and ID1 proteins in the control, NC, PDT, Ad-ALK1 and PDT + Ad-ALK1 groups. *P<0.05, **P<0.01, ***P<0.001 and ****P<0.0001. NC, negative control; Ad, adenovirus; p-, phosphorylated; PDT, photodynamic therapy; ALK1, activin receptor-like kinase-1; ID1, inhibitor of DNA binding 1.