Table 1.
Characteristics of HPV-positive women
| Women (n=4499) | ||
|---|---|---|
| Age, years | ||
| Median | 40·6 (34·7–49·9) | |
| 30–49 | 3378 (75·1%) | |
| 50–65 | 1121 (24·9%) | |
| Ever had a cytology | 4490 (99·8%) | |
| Cytology result at enrolment | ||
| Missing | 130 (2·9%) | |
| Inadequate | 69 (1·5%) | |
| Negative | 3502 (77·8%) | |
| ASC-US | 266 (5·9%) | |
| LSIL | 292 (6·5%) | |
| HSIL+ | 240 (5·3%) | |
| Initial colposcopy (colposcopic impression) | ||
| Normal | 1863 (41·4%) | |
| Positive minor | 2040 (45·3%) | |
| Positive major | 574 (12·8%) | |
| Suspicion of cancer | 22 (0·5%) | |
| TZ type | ||
| TZ1 | 2288 (50·9%) | |
| TZ2 | 1039 (23·1%) | |
| TZ3 | 1172 (26·1%) | |
| Number of biopsies | ||
| 0 | 1759 (39·1%) | |
| 1 | 525 (11·7%) | |
| 2 | 1348 (30·0%) | |
| 3 | 602 (13·4%) | |
| 4 | 265 (5·9%) | |
| Disease outcomes* | ||
| Negative† | 2239 (49·8%) | |
| CIN1 | 1291 (28·7%) | |
| CIN2 | 300 (6·7%) | |
| CIN3‡ | 616 (13·7%) | |
| Cancer | 53 (1·2%) | |
Data are median (IQR) or n (%). ASC-US=atypical squamous cells of undetermined significance. CIN=cervical intraepithelial neoplasia. HSIL=high-grade squamous intraepithelial lesion. LSIL=low-grade squamous intraepithelial lesion. TZ=transformation zone.
*
As detected at the initial or 18-month visit (for participants with less than CIN2 at the initial visit).
†
Includes histologically confirmed negative or normal colposcopy without biopsy at enrolment and at the 18-month follow-up visit.
‡
Includes adenocarcinoma in situ.