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. 2022 May 18;149(4):1569–1583. doi: 10.1007/s00432-022-03995-2

Table 3.

Antifungal strategies at diagnosis dependent on subsequent AML treatment intensity

Palliative treatment Induction chemotherapy
N = 118 N = 102
Antifungal prophylaxis after AML diagnosis
 After IFD, n (%) 9 (7.6) 4 (3.9)
 Posaconazole 2 (1.7) 4 (3.9)
 Voriconazole 4 (3.4)
 Isavuconazole 2 (1.7)
 No prophylaxis 1 (0.8)
 w/o IFD, n (%) 12 (10.2) 94 (92)
 Posaconazole 11 (9.3) 93 (91)
 Voriconazole 1 (0.8)
 Isavuconazol 1 (1)
1st line antifungal treatment
 Liposomal amphotericin 6 (5.1) 2 (2)
 Caspofungin 4 (3.4)
 Posaconazole 2 (1.7)
 Voriconazole 2 (1.7) 2 (2)

AML acute myeloid leukemia, IFD invasive fungal disease