Table 2.
Results of the RCT
| Therapeutic efficacy at EOS | Azithromycin (n = 13) n (%) |
NB-UVB (n = 11) n (%) |
p value | |
|---|---|---|---|---|
| Rash as a whole | Complete response | 3 (23%) | 9 (81.8%) | 0.83 |
| Very-good response | 5 (38.6%) | 1 (9%) | ||
| Good response | 3 (23%) | 0 | ||
| Poor response | 2 (15.4%) | 1 (9%) | ||
| Therapeutic efficacy at EOS | Azithromycin (n = 13) n (%) |
NB-UVB (n = 11) n (%) |
p value | |
|---|---|---|---|---|
| Erythematous Papules | Complete response | 8 (61.5%) | 9 (81.8%) | 0.351 |
| Very-good response | 4 (30.8%) | 0 | ||
| Good response | 0 | 1 (9.1%) | ||
| Poor response | 1 (7.7%) | 1 (9.1%) | ||
| Therapeutic efficacy at EOS | Azithromycin (n = 9) n (%) |
NB-UVB (n = 9) n (%) |
p value | |
|---|---|---|---|---|
| Hypopigmented Lesions | Complete response | 1 (10%) | 8 (88.9) | 0.5 |
| Very-good response | 2 (20%) | 0 | ||
| Good response | 3 (30%) | 0 | ||
| Poor response | 3 (30%) | 1 (11.1%) | ||
| Percent reduction in the extent of rash and extent of rash at EOS | Azithromycin (n = 12) | NB-UVB (n = 10) | p value |
|---|---|---|---|
| Percent reduction in the extent of the rash as a whole (mean ± SD) | 78.13 ± 14.68 | 91.27 ± 13.67 | 0.034* |
| Extent of the rash as a whole at EOS (% body surface) (mean ± SD) | 4.78 ± 4.89 | 1.2 ± 1.9 | 0.029* |
| Percent reduction in the extent of erythematous papules (mean ± SD) | 90.11 ± 10.31 | 88.15 ± 18.24 | 0.785 |
|
Extent of erythematous papules at EOS (% body surface) (mean ± SD) |
1.73 ± 3.31 | 0.66 ± 1.23 | 0.296 |
| Percent reduction in the extent of hypopigmented lesions (mean ± SD) | 62.54 ± 17.53 | 93.3 ± 13.51 | 0.001* |
| Extent of hypopigmented lesions at EOS (% body surface) (mean ± SD) | 3.05 ± 4.66 | 0.54 ± 1.49 | 0.086** |
| Percent reduction in the extent of the rash at weeks 2, 4 and 6 (mean ± SD) | Azithromycin | NB-UVB | p value |
|---|---|---|---|
| At week 2 (n = 24) | |||
| Rash as a whole | 33.33 ± 24.38 | 28.1 ± 13 | 0.512 |
| Erythematous papules | 37.15 ± 27.77 | 27.28 ± 19.28 | 0.318 |
| Hypopigmented lesions | 22.88 ± 26.6 | 39.9 ± 23.9 | 0.173 |
| At week 4 (n = 23) | |||
| Rash as a whole | 55.62 ± 21.38 | 66.85 ± 16.72 | 0.163 |
| Erythematous papules | 68.7 ± 19.57 | 62.26 ± 17.22 | 0.4 |
| Hypopigmented lesions | 42.55 ± 29.22 | 74.56 ± 20.77 | 0.018* |
| At week 6 (n = 23) | |||
| Rash as a whole | 70.04 ± 19.61 | 84.03 ± 13 | 0.049* |
| Erythematous papules | 84.26 ± 14.88 | 81.9 ± 16.53 | 0.720 |
| Hypopigmented lesions | 51.8 ± 20.46 | 86.8 ± 14.27 | 0.001* |
*p value < 0.05 is significant. **Not significant but noticeable result