Figure 2.

Changes of complement markers during the acute and remission phases of neuromyelitis optica spectrum disorders and Guillain-Barré syndrome. Changes of serum levels of sC5b-9, Ba, complement factor H and complement factor I during the acute and remission phases of neuromyelitis optica spectrum disorders and Guillain-Barré syndrome were analyzed. The dotted lines indicate changes in individual cases, and solid lines indicate changes in average levels. The gray shadow indicates reference ranges in healthy Japanese adults (sC5b-9: 181–1266 ng/ml, Ba: 438–1546 ng/ml, complement factor H: 238–663 µg/ml, complement factor I: 11–42 µg/ml) (15). *p < 0.01, paired t-test.