Table 2.
Baseline characteristics of participants with hypertensiona included in meta-analysis for cardiovascular disease analyses (n = 9378).
| Study | Participants at risk of CVD, N |
Simplified Hypertensive Retinopathy Grade |
Participant Characteristics |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| None n (%) | Mild n (%) | Moderate n (%) | Follow-up, median years | Age, mean (SD) years | Female, n (%) | SBP, mean (SD), mmHg | Serum cholesterol, mean (SD), mmol/L | Serum HDL, mean (SD), mmol/L | Current smoker, n (%) | ||
| ARIC | 2811 | 1412 (50.2) | 1270 (45.2) | 129 (4.6) | 9.1 | 60.5 (5.6) | 1675 (59.6) | 137.1 (19.2) | 5.4 (0.9) | 1.4 (0.5) | 425 (15.1) |
| BDES | 1256 | 745 (59.3) | 390 (31.1) | 121 (9.6) | 13.0 | 62.4 (10.3) | 752 (59.9) | 142.4 (19.0) | 6.2 (1.1) | 1.4 (0.5) | 206 (16.4) |
| BMES | 831 | 484 (58.2) | 255 (30.7) | 92 (11.1) | 4.8 | 65.1 (8.6) | 519 (62.5) | 152.9 (16.6) | 6.1 (1.0) | 1.5 (0.4) | 89 (10.7) |
| CHS | 597 | 343 (57.5) | 221 (37.0) | 33 (5.5) | 6.4 | 78.6 (4.1) | 396 (66.3) | 138.4 (20.4) | 5.4 (1.0) | 1.3 (0.4) | 35 (5.9) |
| MESA | 2071 | 1246 (60.2) | 591 (28.5) | 234 (11.3) | 4.8 | 65.4 (9.4) | 1149 (55.5) | 140.1 (20.4) | 5.0 (0.9) | 1.3 (0.4) | 214 (10.3) |
| Rotterdam Study | 1812 | 1266 (69.9) | 419 (23.1) | 127 (7.0) | 11.9 | 68.2 (7.5) | 1150 (63.5) | 140.1 (20.4) | 6.7 (1.2) | 1.4 (0.4) | 326 (18.0) |
| All studies combined | 9378 | 5496 (58.6) | 3146 (33.6) | 736 (7.9) | 7.8 | 64.9 (9.1) | 5641 (60.2) | 142.5 (20.0) | 5.7 (1.2) | 1.4 (0.4) | 1295 (13.8) |
SD, standard deviation; SBP, systolic blood pressures; HDL, high density lipoprotein; ARIC, Atherosclerosis Risk in Communities Study; BDES, Beaver Dam Eye Study; BMES, Blue Mountains Eye Study; CHS, Cardiovascular Health Study; MESA, Multi-Ethnic Study of Atherosclerosis.
Hypertension defined as systolic blood pressure ≥140 mmHg and/or using blood pressure lowering medication.