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. 2023 Mar 3;13:1063178. doi: 10.3389/fphar.2022.1063178

TABLE 6.

Hazard ratios (HR) for progression-free survival in the population with a favorable prognosis.

Intervention [HR (95% CI)]
CAB + NIV AXY + PEM LEN + PEM SUN
Comparator CAB + NIV 1.08 (0.56; 1.65) 0.59 (0.29; 0.94) 1.40 (0.84; 2.00)
AXY + PEM 0.99 (0.52; 1.52) 0.56 (0.30; 0.85) 1.33 (0.94; 1.74)
LEN + PEM 1.85 (0.91; 2.98) 1.91 (1.03; 2.90) 2.49 (1.59; 3.53)
SUN 0.74 (0.45; 1.07) 0.77 (0.55; 1.01) 0.42 (0.27; 0.59)

The values in each cell represent the relative treatment effect for the intervention on the top when compared to the intervention on the left. Green suggests a relative treatment benefit (light green a nonsignificant benefit, and dark green a significant benefit). Red suggests a relative treatment harm (light red a nonsignificant harm, and dark red a significant harm).AXY, axitinib; CAB, cabozantinib; IPI, ipilimumab; LEN, lenvatinib; NIV, nivolumab; PEM, pembrolizumab; SUN, sunitinib