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. 2022 Dec 2;13:1054741. doi: 10.3389/fendo.2022.1054741

Table 1.

Baseline characteristics of participants by TyG index variability quartiles (SD).

Total Q1 Q2 Q3 Q4 P
Participants 48013 12003 12003 12004 12003
Age(years) 48.78 ± 12.05 50.09 ± 12.31 49.36 ± 12.09 48.85 ± 12.05 46.82 ± 11.51 <.01
Male, N (%) 36356 (75.72) 8805(73.36) 8978(74.80) 8989 (74.88) 9584 (79.85) <.01
BMI (kg/m2) 24.84 ± 3.12 24.76 ± 3.15 24.81 ± 3.18 24.87 ± 3.15 24.92 ± 3.00 <.01
SBP (mmHg) 128.55 ± 16.75 128.36 ± 16.93 128.44 ± 16.91 128.66 ± 16.92 128.73 ± 16.22 0.07
DBP (mmHg) 83.19 ± 9.18 82.82 ± 9.15 82.94 ± 9.15 83.25 ± 9.25 83.77 ± 9.15 <.01
HDL-C (mmol/L) 1.54 ± 0.32 1.55 ± 0.32 1.55 ± 0.32 1.54 ± 0.31 1.53 ± 0.32 <.01
LDL-C (mmol/L) 2.48 ± 0.63 2.50 ± 0.63 2.50 ± 0.63 2.48 ± 0.64 2.44 ± 0.63 <.01
FBG (mmol/L) 5.24 ± 0.52 5.09 ± 0.32 5.14 ± 0.60 5.35 ± 0.38 5.49 ± 0.47 <.01
TG (mmol/L) 1.30 (0.96-1.87) 1.21(0.88-1.58) 1.27(0.95-1.81) 1.32 (1.01–1.75) 1.69 (1.14-2.48) <0.01
Hs-CRP (mg/L) 1.42 (0.76-2.83) 1.37 (0.73-2.70) 1.40 (0.76-2.71) 1.43 (0.77-2.92) 1.46 (0.78-3.06) <0.01
TyG index2006 8.55 ± 0.63 8.49 ± 0.50 8.52 ± 0.54 8.52 ± 0.60 8.71 ± 0.77 <.01
TyG index2008 8.57 ± 0.62 8.51 ± 0.50 8.49 ± 0.53 8.56 ± 0.60 8.69 ± 0.80 <.01
TyG index2010 8.61 ± 0.61 8.50 ± 0.51 8.56 ± 0.53 8.64 ± 0.59 8.90 ± 0.75 <.01
Smoking, N (%) 18360 (38.24) 4296.0 (35.79) 4423 (36.85) 4680 (38.99) 4961 (41.33) <.01
Drinking, N (%) 16957 (35.32) 3948 (32.89) 4101 (34.17) 4188 (34.89) 4720 (39.32) <.01
Physical activity, N (%) 6906 (14.38) 1944 (16.20) 1817 (15.14) 1697 (14.14) 1448 (12.06) <.01
Hypertension, N (%) 22072 (45.97) 5391 (44.91) 5444 (45.36) 5563 (46.34) 5674 (47.27) <.01
Antihypertensive drugs, N (%) 6944 (14.46) 1654 (13.78) 1715 (14.29) 1738 (14.48) 1837 (15.30) <.01
Lipid-lowering drugs, N (%) 728 (1.52) 186 (1.55) 178 (1.48) 165 (1.37) 199 (1.66) 0.33
High school or above, N (%) 6217 (12.95) 1599 (13.32) 1606 (13.38) 1583 (13.19) 1429 (11.91) <.01

P, comparison of baseline characteristics between different TyG index variability groups.

TyG index, triglyceride-glucose index; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; FBG, fasting blood glucose; hs-CRP, high-sensitivity C reactive protein.