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. 2022 Dec 2;13:1054741. doi: 10.3389/fendo.2022.1054741

Table 3.

Hazard ratios and 95% Confidence intervals of incident diabetes of TyG index variability (SD).

Case/Total Incidence rate, per 1000 person-years Model 1 Model 2 Model 3
Q1 891/12003 8.80 1.00 1.00 1.00
Q2 933/12003 9.18 1.05(0.96,1.15) 1.04(0.95,1.14) 1.04(0.95,1.14)
Q3 1042/12004 10.28 1.19(1.09,1.30) 1.16(1.06,1.27) 1.13(1.03,1.24)
Q4 1189/12003 11.70 1.39(1.27,1.51) 1.34(1.23,1.47) 1.18(1.08,1.29)
1-SD increase (0.22) 1.20(1.09,1.15) 1.11(1.08,1.15) 1.04(1.01,1.07)
P for Trend <0.0001 <0.0001 <0.0001

Model 1: adjusted for age (continuous variable, years) and sex (categorical variable, men or women) in 2010.

Model2: included variables in model 1 and further LDL-C (as a continuous variable), HDL-C (as a continuous variable), hs-CRP (as a continuous variable), BMI (as a continuous variable), smoking status (as a categorical variable, yes or no), alcohol consumption status (as a categorical variable, yes or no), physical exercise habits (as a categorical variable, yes or no), educational level (as a categorical variable, high school or above vs. below high school level), hypertension (as a categorical variable, yes or no), and the use of lipid-lowering drugs (as a categorical variable, yes or no) in 2010.

Model 3: included variables in model 2 and further the TyG index (continuous variable) in baseline.