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. 2022 Dec 2;13:1054741. doi: 10.3389/fendo.2022.1054741

Table 4.

Hazard ratios and 95% Confidence intervals of incident of TyG index in subgroup ratio variability (SD).

Age (P for interaction 0.33) Sex (P for interaction 0.16) TyG index change slop(P for interaction 0.74)
<45 years ≥ 45 years Female Male >0 ≤0
Quartiles
Q1 1.00 1.00 1.00 1.00 1.00 1.00
Q2 1.09 (0.92,1.30) 1.02 (0.93,1.12) 1.07 (0.88,1.30) 1.03 (0.93,1.15) 0.93 (0.81,1.05) 1.16 (1.01,1.32)
Q3 1.23 (1.06,1.50) 1.07 (0.96,1.19) 1.18 (0.98,1.43) 1.11 (1.01,1.24) 0.98 (0.94,1.01) 1.28 (1.13,1.46)
Q4 1.25 (1.06,1.46) 1.11 (1.00,1.24) 1.36 (1.12,1.65) 1.14 (1.02,1.25) 1.06 (1.01,1.11) 1.50 (1.32,1.70)
P for trend <0.01 0.04 0.02 <0.01 <0.01 <0.01

Adjusted for age (continuous variable, years), sex (categorical variable, men or women), LDL-C (as a continuous variable), HDL-C (as a continuous variable), hs-CRP (as a continuous variable), BMI (as a continuous variable), smoking status (as a categorical variable, yes or no), alcohol consumption status (as a categorical variable, yes or no), physical exercise habits (as a categorical variable, yes or no), educational level (as a categorical variable, high school or above vs. below high school level), hypertension (as a categorical variable, yes or no), the use of lipid-lowering drugs (as a categorical variable, yes or no) in 2010, and TyG index (continuous variable) in baseline.