Table 5.

Sensitivity analysis of the association of TyG index variability with incident diabetes.

	Sensitivity analysis 1	Sensitivity analysis 2	Sensitivity analysis 3	Sensitivity analysis 4
Q1	1.00	1.00	1.00	1.00
Q2	1.04 (0.95,1.14)	1.02 (0.93,1.12)	1.11 (0.98,1.26)	1.03 (0.94,1.13)
Q3	1.13 (1.03,1.24)	1.13 (1.03,1.24)	1.17 (1.03,1.33)	1.13 (1.03,1.23)
Q4	1.18 (1.08,1.29)	1.19 (1.06,1.28)	1.42 (1.25,1.62)	1.22 (1.12,1.34)
P for Trend	<0.0001	0.0002	<0.0001	<0.0001

Adjusted for age (continuous variable, years), sex (categorical variable, men or women), LDL-C (as a continuous variable), HDL-C (as a continuous variable), hs-CRP (as a continuous variable), BMI (as a continuous variable), smoking status (as a categorical variable, yes or no), alcohol consumption status (as a categorical variable, yes or no), physical exercise habits (as a categorical variable, yes or no), educational level (as a categorical variable, high school or above vs. below high school level), hypertension (as a categorical variable, yes or no), the use of lipid-lowering drugs (as a categorical variable, yes or no, except sensitivity analysis 2), and TyG index (continuous variable) in baseline.

Sensitivity analysis 1: the exclusion of participants in whom diabetes developed within the first year of follow-up.

Sensitivity analysis 2: the exclusion of participants who were taking lipid-lowering or antihypertensive medication.

Sensitivity analysis 3: the exclusion of participants with TG ≥ 2.3 mmol/L in baseline.

Sensitivity analysis 4: adjusting for the baseline TG and FBG and without the inclusion of the baseline TyG-index.