Table 6.
Factors influencing high-dose opioid cases for titration response (multiple logistic regression)
| Variable | Univariate model | Multivariate model | ||
|---|---|---|---|---|
| Odds Ratio (95% CI) | P value | Odds Ratio (95% CI) | P value | |
| Age | 1.056 (1.012–1.102) | .012 | 1.053 (1.003–1.105) | .036 |
| Sex | 1.856 (0.887–3.885) | .101 | ||
| Performance status | 1.038 (0.682–1.578) | .863 | ||
| Opioid regimen | 2.862 (−0.076 to 1.206) | .005 | 3.818 (1.664–8.763) | .002 |
| Neuropathic pain | 1.015 (0.976–1.054) | .461 | ||
| rs4680 genotype | 0.939 (0.460–1.917) | .863 | ||
| Pretreatment NRS | 1.423 (1.179–1.717) | <.001 | 1.445 (1.175–1.777) | <.001 |
| Pretreatment HADS | 1.018 (0.970–1.069) | .471 | ||
Abbreviations: HADS, Hospital Anxiety and Depression Scale; NRS, numerical rating scale.