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. 2023 Mar 2;9:e42350. doi: 10.2196/42350

Table 3.

Annual medical expense of the cancer and comparison groups.a


Study group
Category Childhood cancer survivors (n=33,105) Cancer groups (ICD-9-CMb) Comparison group


Hematologic cancer (200-208) (n=3934) Brain cancer (191-192) (n=2241) Benign brain tumor (225) (n=7825) Non-CNSc solid tumor (140-190; 193-199) (n=19,105) P valued No cancer individuals (n=64,754) P valuee
Total expense 285.56 (161.78-535.80) 268.48 (159.50-475.08) 614.08 (267.05-1793.94) 336.89 (184.64-652.14) 257.78 (148.44-456.88) <.001 203.90 (118.98-347.55) <.001
Outpatient 239.81 (140.24-416.02) 230.96 (138.51-368.64) 473.60 (223.04-1380.48) 274.76 (159.54-503.51) 219.49 (129.69-362.93) <.001 174.50 (103.38-280.90) <.001

Hospital outpatient 50.94 (10.46-165.40) 45.48 (10.93-132.53) 227.17 (42.62-1076.80) 75.48 (18.91-236.87) 39.37 (6.98-124.60) <.001 20.56 (3.19-67.82) <.001

Community clinic 150.78 (89.09-237.73) 148.16 (92.35-232.70) 172.90 (93.45-284.81) 156.97 (91.28-248.53) 146.74 (87.16-230.49) <.001 131.03 (76.53-206.54) <.001
Inpatient 0.00 (0.00-36.49) 0.00 (0.00-30.92) 0.00 (0.00-142.36) 0.00 (0.00-72.10) 0.00 (0.00-0.00) <.001 0.00 (0.00-0.00) <.001
Emergency 8.45 (0.00-26.50) 7.87 (0.00-23.44) 14.29 (0.00-44.84) 10.54 (0.00-32.22) 7.25 (0.00-23.59) <.001 5.31 (0.00-19.02) <.001
Regional hospital 71.91 (19.90-235.61) 61.90 (18.78-183.95) 278.41 (64.85-946.18) 107.37 (30.41-314.84) 57.08 (15.07-178.88) <.001 34.40 (8.50-109.28) <.001
Medical center 6.35 (0.00-67.90) 6.93 (0.00-60.93) 68.37 (0.00-598.16) 13.52 (0.00-107.51) 2.82 (0.00-44.52) <.001 0.00 (0.00-17.78) <.001

aData are presented as median expense in US $ per person per year (IQR).

bICD-9-CM: International Classification of Diseases, Ninth Revision, Clinical Modification.

cCNS: central nervous system.

dCompared among the cancer groups and the no cancer group.

eCompared between all cancer survivors versus no cancer individuals.