. 2023 Feb 22;14(6):1080–1094. doi: 10.1021/acschemneuro.2c00476

Table 1. Residence Time of Small Molecule Compound 1, AZ1080, and BRD0705 for GSK3α and GSK3β^a.

K_observed(normalized to DMSO)
compound	GSK3α	GSK3β
AZ1080	1.08	1.13
BRD0705	1.05	1.04
compound 1	1	0.91

There was no difference in the residence time of the novel compound 1 at either GSK3α or GSK3β when compared to the previously profiled compounds AZ1080 or BRD0705.

Table 1. Residence Time of Small Molecule Compound 1, AZ1080, and BRD0705 for GSK3α and GSK3βa.

Table 1. Residence Time of Small Molecule Compound 1, AZ1080, and BRD0705 for GSK3α and GSK3β^a.