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Epigenetic landscape of the HCMV genome at 4 and 24 hpi. RNA-seq (purple), Pol II ChIP-seq (pink), H3K27Ac ChIP-seq (green), and H3K27me ChIP-seq (red) coverage maps for the entire HCMV genome (A) and zoom-in image for the MIEP (B) and oriLyt (C) regions in Kasumi-3 infected cells at 4 and 24 hpi. A representative example of three independent experiments is shown. (D) PCR-ChIP analyses of the MIEP and oriLyt regions at 4 and 24 hpi. Three biological replicates were analyzed.
